Whether you are specifically looking for an RPG about evolution or just something different, EVO is one worth recommending.
If you are looking for an interesting 2-player game that combines puzzle platforming and tower defense, Aegis Defenders is not a bad choice.
Around the early 2010s, there was a surge of indie games with retro graphics and gameplay. Rogue Legacy gives its take on the roguelike genre.
Faxanadu puts you in the head of an adventurer who has to rise up and carry on in the place where other potential heroes have fallen.
Brave Fencer Musashi feels like it tried to do a bunch of things, but bit off way more than it could chew.